Journal Information

  • ISSN
  • Focus and scope
  • Publication frequency
  • Types of articles published
  • Open access
  • Review process
  • Historic data
  • Marketing
  • Membership



2519-7533 (ONLINE)

2412-2785 (PRINT)

Focus and scope

The Journal of Insulin Resistance is a peer-reviewed, clinically oriented journal covering advances in disorders of insulin resistance. Articles will focus on clinical care and advancing therapy for patients with insulin resistance related disorders, such as obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, non-alcoholic steato-hepatitis, Alzheimer’s dementia, sexual dysfunction and other related disorders. Insulin Resistance includes pathophysiology, management, patient education, and treatment considerations for different patient populations.

The journal will feature original research, reviews, editorials, case studies, and patient handouts.

This will be of interest to medical practitioners, clinical educators, nurse practitioners and other health care professionals involved in the care of patients with disorders related to insulin resistance.

Submissions in English (full article) will be considered for publication.

Publication frequency

The journal publishes at least one issue each year. Articles are published online when ready for publication and then printed in an end-of-year compilation. Additional issues may be published for special events (e.g. conferences) and when special themes are addressed.

Types of articles published

The following types of articles are accepted by the journal:

  • Original research: An original article provides an overview of innovative research in a particular field within or related to the focus and scope of the journal, presented according to a clear and well-structured format (3500-7000 words with a maximum of 60 references). Compulsory as a supplementary file: Ethical clearance letter/certificate.

    Systematic reviews should follow the same basic structure as other original research articles. The aim and objectives should focus on a clinical question that will be addressed in the review. The methods section should describe in detail the search strategy, criteria used to select or reject articles, attempts made to obtain all important and relevant studies and deal with publication bias (including grey and unpublished literature), how the quality of included studies was appraised, the methodology used to extract and/or analyse data. Results should describe the homogeneity of the different findings, clearly present the overall results and any meta-analysis.
  • Literature review articles: The review article presents a critical review of the literature on a topic that has both social and scientific value, and which is within the focus and scope of the journal (between 2500–4000 words with a maximum of 60 references). Systematic reviews are considered under original research.
  • Scientific letter: Original research that is limited in scope can be submitted as a scientific letter rather than a full original research article. A scientific letter should be no more than 800 words, 15 references, and 1 table or figure.
  • Letters to the editor: Should be about 400 words with only one illustration or table, and must include a correspondence address. They may be subjected to the peer review process and their eventual placement is at the discretion of the editorial team. 
  • Obituaries: Should be about 400 words and may be accompanied by a photograph
  • Editorials: Editorials are by invitation only and are intended to provide expert comment on relevant topics within the focus and scope of the journal. (Less than 800 words with a maximum of 10 references).
  • Conference report: This allows the author to submit a report on a national or international conference relevant to the focus and scope of the journal. Conference reports should be no longer than 1500 words
  • Conference proceedings and abstracts: Such manuscripts may be published by the journal. Should you wish that the journal publish proceedings from a conference you are organising, please contact the Editor.

See more specifications for the types of articles published here

Open access

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access. Learn more about the journal copyright, licensing and publishing rights.

Review process

The journal has a double-blinded peer review process. Manuscripts are initially examined by editorial staff and are sent by the Editor-in-Chief to two expert independent reviewers, either directly or by a Section Editor. Read our full peer review process.

Historic data

AOSIS launched the Journal of Insulin Resistance (JIR) in 2015, following a unique conference that was held in Cape Town during 19-22 February 2015 (“The Old Mutual Health Convention”) to discuss the global obesity epidemic and its co-morbidity of lifestyle diseases.

The invitation to the conference stated:

“The world is facing a tsunami of lifestyle-related chronic diseases that will cost our global economy $47 trillion over the next twenty years. These diseases are eminently preventable and treatable, and yet currently, every year, they kill twice as many people around the world as infectious diseases do. According to the Centers for Disease Control (CDC), in America, more than 1/3 of adults are obese as are approximately 12.5 million children. In South Africa our nation’s battle with the bulge is fast becoming a health epidemic. A survey by global healthcare company GlaxoSmithKline earlier this year confirmed that at least 60% or nearly two out of every three South Africans are overweight, obese or morbidly obese…….. Clearly, what we have been taught is not working. We need a different paradigm. We need a different model.”

During the conference it became clear that the current nutritional guidelines clearly is not working as the prevalence of obesity and especially diabetes is ever increasing in spite of these guidelines, to which people and food producers generally kept well. These guidelines, promoting a “high carbohydrate-low-fat” diet, are based on the premise that the cause of obesity is eating too many calories (with fatty foods the main culprit as they are the most energy dense, and they are also dangerous because they cause high cholesterol and cardiovascular disease) and not exercising enough to burn off the calories eaten. It was also proposed that the scientific evidence for these guidelines was fatally flawed and largely absent. The guidelines and what followed was tantamount to a large scale population experiment, based on poor evidence, which failed with dire consequences.

The alternative model to obesity was proposed to be the hormonal model, i.e. that a high carbohydrate diet causes chronically elevated insulin levels, leading to insulin resistance, which is driving obesity. It was also argued that the evidence that saturated fat in the diet is the cause of cardiovascular disease was flawed, and that saturated fat in fact is healthier than carbohydrates as a source of energy, and not contributing to obesity. They key metabolic “fault” driving obesity was proposed to be insulin resistance, with an underlying genetic propensity in the majority of people.

It became clear that the scientific field of “insulin resistance”, viz. its pathophysiology, morbidity (e.g. obesity, metabolic syndrome, type 2 diabetes, non-alcoholic steato-hepatitis, Alzheimer’s dementia), management, education and treatment must be a key area for research, academic discourse and education of health professionals. It has to be part of the solution.

Although there are many journals focusing on nutrition, obesity and endocrinology they are also focused on the prevailing “calories in calories out” and “fat is bad” paradigms, and most are not published in open access, limiting accessibility.

It was concluded that a journal is needed to focus on this new paradigm, the alternative hormonal model underlying obesity and insulin resistance.


AOSIS has a number of ways in which we promote publications. Learn more here.


AOSIS is a member and/or subscribes to the standards and code of practices of several leading industry organisations. This includes the Directory of Open Access Journals, Ithenticate, Open Access Scholarly Publishers Association, CrossRef, Portico and the Committee on Publication Ethics (COPE). Learn more here.

DHET accreditation

The journal is not yet DHET accredited. Application is in progress.

Indexing Services

All articles published in the journal are included in:

  • GALE, CENGAGE Learning

We are working closely with relevant indexing services to ensure that articles published in the journal will be available in their databases when appropriate.


The full text of the journal articles is deposited in the following archives to guarantee long-term preservation:

  • Portico
  • AOSIS Library
  • South African Government Libraries

AOSIS is also a participant in the LOCKSS (Lots of Copies Keep Stuff Safe) initiative. LOCKSS will enable any library to maintain their own archive of content from AOSIS and other publishers, with minimal technical effort and using cheaply available hardware.

The URL to the LOCKSS Publisher Manifest for the journal is: 
Please inform us if you are using our manifest as we would like to add your name to the list above.

Journal impact

A journal's Impact Factor was originally designed in 1963 as a tool for libraries to compare journals, and identify the most popular ones to subscribe to. It was never intended to measure the quality of journals, and definitely not the quality of individual articles.

The Impact Factor is a journal-level measurement reflecting the yearly average number of citations of recent articles published in that journal. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher Impact Factors are often deemed to be more important than those with lower ones. Therefore, the more often articles in the journal are cited, the higher its Impact Factor.

The Impact Factor is highly discipline-dependent due to the speed with which articles get cited in each field and the related citation practices. The percentage of total citations occurring in the first two years after publication varies highly amongst disciplines. Accordingly, one cannot compare journals across disciplines based on their relative Impact Factors.

We provide several citation-based measurements for each of our journals, if available. We caution our authors, readers and researchers that they should assess the quality of the content of individual articles, and not judge the quality of articles by the reputation of the journal in which they are published.

Citation-based measurement


Journal Impact Factor, based on Web of Science (formerly ISI)


CiteScore, based on Scopus, Elsevier


Source-Normalized Impact per Paper (SNIP), based on Scopus, Elsevier


Scimago Journal Rank (SJR), based on Scopus, Elsevier


H-index, based on Google Scholar



*Journal launched in 2016.